Changing the audio device while using Audio Splitting can cause the feature to stop working with newly launched applications that use the audio.
Making changes to the audio device such disconnecting and reconnecting headphones can cause the audio splitting feature to fail for any new applications used that make use of audio.
While we work on a fix for this issue we recommend that you do not disconnect your headphones or other sound devices while using audio splitting, if you do need to disconnect the device for any reason just restart SuperNova to prevent any audio issues.